Multidisciplinary Acute Care Research Organization

The Multidisciplinary Acute Care Research Organization (MACRO) is a joint clinical trials enterprise focusing on acute care and led by the Departments of Critical Care Medicine, Surgery, Emergency Medicine, and the Division of Pulmonary, Allergy, and Critical Care Medicine. MACRO's overall mission is to facilitate clinical research in an ethical, fiscally sound, and regulatory compliant manner. MACRO provides resources for investigators and participants in acute care settings including the emergency department, ICU, and operating room.

A key service provided by MACRO is 24/7 screening and enrollment of research participants. In addition to coordinating numerous studies over multiple departments and divisions, MACRO also serves as overall coordinating center for five multicenter trials, including the large (DoD) LITES project, a research network linking U.S. trauma centers. MACRO also supports two large NIH trial networks (NETT, PETAL). Additional information about MACRO and currently enrolling studies can be found here.

• Grant application support
• Protocol implementation and execution
• Consultation on protocol design
• Regulatory expertise
• Project management and coordinating center services
• Recruitment of research patients in acute care settings
• Trained clinical research coordinators and around-the-clock research assistants